Square One Publishers focuses on publishing adult nonfiction books. They are looking for books by authors that are experts in their field. Their books are focused on meeting the needs of niche audiences. They are not a publisher of bestsellers, they have a specific market/markets and they cater to them.
Currently they are open to submissions about parenting, alternative health, personal finance, collectables, cooking, gambling, postcards, health, self-help, writing, and how to. They are based out of New York. They also publish memoir but are not currently open to unsolicited submissions of it.
They have been around for a while and they focus on print work. They seem to understand the markets they focus on and have a fair grasp of their readers. They were founded in 2000 by former Avery Publishing Group president Rudy Shur, and all of their editors had previous publishing experience before joining Square One. They appear to have a strong grasp of marketing.
It is important to browse their catalog so you can get a better feel for what they have previously published. You can do so here.
When you submit, make sure to include a detailed cover letter outlining the book and its intended audience as well as a table of contents and an overview of the book. The submission packet should also include biographical information about you and any additional contributors. All submissions must be made by post and you must include a self-addressed and stamped envelope.
To learn more or to submit, visit their submissions page here.